Summary:
This study explored the anticancer potential of medicinal plants from Nepal, leveraging the country’s rich biodiversity and abundance of phytochemicals. Crude methanolic extracts were prepared primarily from dried leaf parts, followed by phytochemical screening and quantitative estimation of phenolic and flavonoid content. Antioxidant activity was assessed using DPPH free radical scavenging assays. The extracts were further evaluated for anticancer activity through cell proliferation inhibition and apoptosis assays on a triple-negative breast cancer (TNBC) cell line (MDA-MB-231). The research highlights the value of Nepalese medicinal plants as potential sources of bioactive compounds with therapeutic relevance against cancer.
Project Year: 2017
Student: Asbin Bahadur Chand
External supervisor: Dr. Deena Shrestha
College: Tribhuvan University
Project Status: Completed